Process for the production of human interferon

C - Chemistry – Metallurgy – 07 – K

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167/103.1

C07K 14/555 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1135186

ABSTRACT OF THE DISCLOSURE The present invention relates to processes for an easily carried out industrial production of interferon and the use of the product for preventing and treating interferon- sensitive diseases. Instead of inoculating and culturing established human cells in a culture medium in vitro, the present invention provides for transplating established human cells to other warm-blooded animals or inoculating the cells in a diffusion chamber, multiplying the cells therein while allowing the animals to supply the cells with their nutrient body fluids, and exposing in vivo or in vitro the resultant cells to the action of an interferon inducer to produce easily a large amount of interferon. The present invention is also based on the discovery that the interferon obtained by the method disclosed herein is an effective and superior preparation for preventing and treating interferon-sensitive diseases.

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