Process for the production of levorphanol and related compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 221/28 (2006.01)

Patent

CA 2577406

A process for the production of morphinans with higher purity and yield, when compared to the conventional process, is described. Specifically, the process may be used to prepare levorphanol, levorphanol tartrate, and levorphanol tartrate dihydrate in high yields and substantially free from several process impurities.

Cette invention concerne un procédé de fabrication de morphinanes qui marque un progrès par rapport au procédé classique en termes de pureté et de rendement. Ce procédé convient en particulier pour la fabrication à fort rendement de lévorphanol, de lévorphanol tartrate et de lévorphanol tartrate dihydrate pratiquement exempts de diverses impuretés de fabrication.

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