C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/278.1, 260/3
C07D 403/06 (2006.01) C07D 249/08 (2006.01)
Patent
CA 1074313
ABSTRACT OF THE DISCLOSURE The invention relates to processes for the production of new triazole derivatives of the general formula Image (1) wherein R1 represents hydrogen, lower alkyl, hydroxymethyl, lower alkanoyloxy methyl, lower alkoxy methyl, formyl, car- boxy, lower alkoxy carbonyl, cyano or a group of the partial formula I aa Image (I aa) in which X represents oxygen or two hydrogen atoms and R4 and R5 each independently represent hydrogen, lower alkyl having at most 3 carbon atoms, or together with the adjacent nitrogen atom, they represent mor- pholino, 1-pyrrolidinyl, or piperidino, R2 represents lower alkyl, R3 represents hydrogen or lower alkyl or together with the adjacent nitrogen atom they represent morpholino, 1-pyrrolidinyl or piperidino the rings A and B independently of each other are unsub- stituted or substituted by halogen up to atomic number 35, trif1uoromethyl, nitro, lower alkyl or lower alkoxy and their addition salts. These new substances possess valuable pharmacological properties. In particular they have an anticonvulsive activity and are useful as active substances for therapeutic prepara- tions for the treatment of epilepsy and of conditions of tension and of agitation.
229230
Heckendorn Roland
Meier Rene
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