Process for the production of optically active cyclic...

C - Chemistry – Metallurgy – 07 – C

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C07C 221/00 (2006.01) C07C 225/20 (2006.01) C07D 215/38 (2006.01) C07F 9/6574 (2006.01)

Patent

CA 2390921

A process for the production of optically active cyclic enaminone derivatives, characterized by aminating one of the carbonyl groups of a cyclic 1,3-diketone derivative having a symmetry plane to thereby obtain an optical isomer mixture of a chiral cyclic enaminone derivative and subjecting this mixture to optical resolution.

L'invention concerne un procédé de production de dérivés d'énaminone cycliques optiquement actifs, caractérisé par les étapes consistant à : aminer l'un des groupes carbonyle d'un dérivé de 1,3-dicétone cyclique comportant un plan de symétrie pour obtenir un mélange d'isomères optiques contenant un dérivé d'énaminone cyclique chiral ; et soumettre ce mélange à une résolution optique.

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