Process for the production of optically enriched (r)- or...

Details Process for the production of optically enriched (r)- or... Process for the production of optically enriched (r)- or...

C - Chemistry, Metallurgy

07

D

C07D 319/08 (2006.01) C07B 55/00 (2006.01) C07C 213/10 (2006.01) C07C 215/60 (2006.01)

Patent

CA 2320756

A process for the production of optically enriched (R)- or (S)-albuterol or (R)- or (S)-albuterol salts by the resolution of a novel ketal derivative 2-(N-t-butylamino)-1-(+2,2-dimethyl-1,2-benzodioxin-6-yl) ethanol, with a chiral tartaric acid derivative.

On décrit un procédé de production d'albutérol (R) ou (S) optiquement enrichi ou de sels d'albutérol (R) ou (S) qui s'effectue au moyen de la résolution d'un nouveau dérivé cétal 2-(N-t-butylamino)-1-(+2,2-diméthyl-1,2-benzodioxin-6-yl)éthanol, avec un dérivé d'acide tartrique chiral.

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