Process for the production of phospholipids

Details Process for the production of phospholipids Process for the production of phospholipids

C - Chemistry, Metallurgy

12

P

C12P 9/00 (2006.01) C12P 13/00 (2006.01) C12P 13/06 (2006.01) C12P 19/44 (2006.01)

Patent

CA 2417597

A process for the production of phospholipids by transphosphatidylation, which comprises the step of mixing a starting phospholipid with a receptor having one or more hydroxyl groups, phospholipase D and water in the absence of an organic solvent and homogenizing the resulting mixture and the step of subjecting the obtained homogeneous mixture to a reaction at 15 to 65~C. The homogeneous mixture has a lamellar lyotropic liquid crystal structure and can give an objective phospholipid via transphosphatidylation without using an organic solvent or calcium.

La présente invention concerne un processus de production de phospholipides par transphosphatidylation, qui consiste à mélanger un phospholipide de départ avec un récepteur possédant un ou plusieurs groupes hydroxyle, une phospholipase D et de l'eau en l'absence de solvant organique, à homogénéiser le mélange résultant et à soumettre le mélange homogène obtenu à une réaction sous une température allant de 15?0¿C à 65?0¿C. Ce mélange homogène possède une structure de cristal liquide lyotropique laminaire et il peut donner un phospholipide objectif via une transphosphatidylation sans utilisation de solvant organique ni de calcium.

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