C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/04 (2006.01) C07D 239/42 (2006.01)
Patent
CA 2057751
ABSTRACT OF THE DISCLOSURE A process is disclosed for the production of piperazinylpyrimidine derivatives of the formula: Image (I) wherein R1 is a hydrogen atom or a branched or unbranched C1-C4 alkyl group. Piperazine or the hydrate thereof is reacted with cyanamide in an acidic medium to form an amidine salt which is then reacted with a carbonyl compound, in the presence of a base, to form the desired end product.
G. Ronald Bell & Associates
Lonza Ltd.
LandOfFree
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