Process for the production of rapidly disintegrating...

Details Process for the production of rapidly disintegrating... Process for the production of rapidly disintegrating...

A - Human Necessities

61

K

A61K 9/70 (2006.01) A23G 3/00 (2006.01) A23G 3/34 (2006.01) A23L 1/22 (2006.01) A23P 1/08 (2006.01) A61K 8/02 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2044043

A presentation which, in the form of a film, permits the individual dosage of drugs, confectionary, other food, cosmetics and the like for oral application or intake. The presentation is characterized by the fact that it comprises a mass of 20 to 60%-wt. of at least a film former, 2 to 40X-wt. of at least a gel former, 0.1 to 35%-wt. of at least an active substance, and up to 40%-wt. of an inert filling agent, being applied on a carrier, or by consisting of a mass having the aforementioned composition but is unsupported. In the production thereof, an intimate mixture of said components is prepared, optionally with the addition of up to 30%-wt. of a polar solvent, and processed to form a homogeneous, spreadable or extrudable mass.

Une présentation qui, sous forme de pellicule, permet l'application orale ou l'ingestion de quantités individuelles de médicaments, de friandises, d'autres aliments, de cosmétiques, etc. La présentation se caractérise par le fait qu'elle contient de 20 à 60 % (en masse) d'au moins une substance filmogène, de 2 à 40 fois cette masse d'au moins un gélifiant, de 0,1 à 35 % d'au moins une substance active et jusqu'à 40 % de charge inerte, appliquée sur un vecteur, ou d'une masse ayant la composition déjà mentionnée, mais sans support. Pour la production de cette présentation, un mélange intime desdites composantes est préparé, possiblement avec l'addition d'une concentration de solvant polaire allant jusqu'à 30 % (en masse), et transformé de façon à former une masse homogène étalable ou extrudable.

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