Process for the production of semi synthetic statins via...

C - Chemistry – Metallurgy – 07 – D

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C07D 309/30 (2006.01) C07C 235/26 (2006.01) C07C 235/30 (2006.01) C07D 319/06 (2006.01) C07D 327/10 (2006.01) C07F 5/02 (2006.01) C07F 9/6574 (2006.01)

Patent

CA 2278603

A process has been provided to produce semi synthetic statins, as for instance simvastatin with a high yield, from another statin, preferably a naturally occurring statin, as for instance lovastatin. Also a number of novel intermediate compounds, prepared during said process, has been provided.

L'invention concerne un procédé de production à fort rendement de statines semi-synthétiques, comme par exemple la simvastatine, à partir d'une autre statine, de préférence une statine naturelle, comme par exemple la lovastatine. L'invention concerne également un certain nombre de nouveaux composés intermédiaires, préparés au cours de ce procédé.

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