A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/164, 167/228
A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 31/44 (2006.01) A61K 31/74 (2006.01)
Patent
CA 1146866
ABSTRACT OF THE DISCLOSURE Sustained release pharmaceutical compositions of solid medical material contains the amorphous solid medical material, polyethylene oxide, and at last one basic substance selected from the group consisting of hydroxy- propylmethyl cellulose, hydroxypropyl cellulose, methyl cellulose, polyvinyl pyrrolidone, carboxyvinyl polymer, hydroxypropylmethyl cellulose phthalate, cellulose acetate phthalate, methyl meta-acrylate meta-acrylic acid copolymer, polyvinylacetal diethylaminoacetate, dimethylaminoethyl meta-acrylate metal acrylic acid copolymer, 2-methyl-5- vinylpyridinemethyl acrylate meta-acrylic acid copolymer, citric acid, urea, succinic acid and amino acid. Optionally, the composition may further contain another basic substance selected from the group consisting of surface active agent, polyethylene glycol, propylene glycol, glycerin, glycerin fatty acid ester and vegetable oil. According to another aspect of the invention, a sustained release pharmaceutical composition of amorphous nicardipine compounded with polyethylene oxide is provided.
354396
Aruga Masayoshi
Kawata Hiroitsu
Ohmura Tadayoshi
Sone Chiharu
Sonobe Takashi
Johnson Douglas S. Q.c.
Yamanouchi Pharmaceutical Co. Ltd.
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