Process for the production of tert-butyl (e)-(6-[2-...

Details Process for the production of tert-butyl (e)-(6-[2-... Process for the production of tert-butyl (e)-(6-[2-...

C - Chemistry, Metallurgy

07

F

C07F 9/6512 (2006.01) C07D 239/42 (2006.01) C07D 405/06 (2006.01)

Patent

CA 2362594

The invention concerns a process for the manufacture of tert-butyl (E)-(6-[2-4- (4-fluorophenyl)-6-isopropyl-2-[methyl(met hylsulfonyl)amino]pyrimidin-5-yl]vinyl}-(4R, 6S)-2,2-dimethyl [1,3-dioxan-4- yl)acetate, the novel starting material used in said process and the use of the process in the manufacture of a pharmaceutical.

L'invention porte sur un procédé de fabrication de <u>tert</u>-butyl (E)-(6-{2- [4-(4-fluorophényl) -6-isopropyl-2-[ méthyl (méthylsulfonyl) amino]pyrimidin-5- yl]vinyl}-(4R, 6S)-2,2-diméthyl[1, 3-dioxan-4-yl) acétate, sur le nouveau précurseur utilisé dans ce procédé, et sur l'utilisation dudit procédé pour la fabrication de produits pharmaceutiques.

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