C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/00 (2006.01) B01D 15/38 (2006.01) B01J 20/281 (2006.01) C07K 1/22 (2006.01)
Patent
CA 2738789
The present invention relates to a novel process for the purification of antibodies, e.g. monoclonal antibodies. The process utilizes an affinity resin comprising a solid phase material having immobilized thereto one or more low-molecular weight synthetic ligands. The affinity resins enable the separation of antibodies from even closely related proteins.
La présente invention concerne un nouveau procédé de purification d'anticorps, par exemple d'anticorps monoclonaux. Le procédé utilise une résine d'affinité comportant une matière en phase solide ayant immobilisés sur celle-ci un ou plusieurs ligands synthétiques de faible masse moléculaire. Les résines d'affinité permettent la séparation d'anticorps de protéines même lorsquelles sont étroitement liées.
Nielsen Anders Laerke
St. Hilaire Phaedria Marie
Dimock Stratton Llp
Novo Nordisk A/s
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