Process for the purification of non-ionic solvents for...

C - Chemistry – Metallurgy – 11 – B

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C11B 3/00 (2006.01) A61K 47/44 (2006.01) C11B 3/10 (2006.01)

Patent

CA 2532110

A stabilized pharmaceutical composition of anticancer drug and a solvent like Polyethoxylated castor oil (cremophor) also containing any other suitable solubilizer suitable for human administration like dehydrated alcohol, is disclosed. Compositions prepared using this purified polyethoxylated castor oil enhance the stability of paclitaxel in such compositions.

L'invention concerne une composition pharmaceutique stabilisée contenant un médicament anticancéreux et une huile de ricin polyéthoxylée (crémophore) de type solvant contenant également un solubilisant de type alcool déshydraté pouvant être administré à un humain. Les compositions préparées à base de cette huile de ricin polyéthoxylée purifiée améliorent la stabilité du paclitaxel contenu dans ces compositions.

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