C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 315/04 (2006.01) C07C 317/28 (2006.01)
Patent
CA 2409139
Disclosed is a process for selectively reducing a nitrile containing organic compound of formula (II) (in which R and R1 are independently lower alkyl, cycloalkyl, aryl, heteroaryl, arylalkyl, or heteroarylalkyl; and n is 0-6) that also contains a sulphone moiety, the nitrile being reduced to a primary amine by use of borane or a substituted borane at a temperature of about -10 ~C to 60 ~C.
L'invention concerne un procédé permettant de réduire sélectivement un composé organique contenant un nitrile ainsi qu'une fraction sulfone, ledit nitrile étant réduit en une amine primaire.
Hwang Chankou
Piscopio Anthony D.
Tarlton Eugene
Array Biopharma Inc.
Hwang Chankou
Mbm & Co.
Piscopio Anthony D.
Tarlton Eugene
LandOfFree
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