Process for the reduction of cyano-substituted sulfones to...

Details Process for the reduction of cyano-substituted sulfones to... Process for the reduction of cyano-substituted sulfones to...

C - Chemistry, Metallurgy

07

C

C07C 315/04 (2006.01) C07C 317/28 (2006.01)

Patent

CA 2409139

Disclosed is a process for selectively reducing a nitrile containing organic compound of formula (II) (in which R and R1 are independently lower alkyl, cycloalkyl, aryl, heteroaryl, arylalkyl, or heteroarylalkyl; and n is 0-6) that also contains a sulphone moiety, the nitrile being reduced to a primary amine by use of borane or a substituted borane at a temperature of about -10 ~C to 60 ~C.

L'invention concerne un procédé permettant de réduire sélectivement un composé organique contenant un nitrile ainsi qu'une fraction sulfone, ledit nitrile étant réduit en une amine primaire.

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