Process for the separation and production of chlorogenic acid

Details Process for the separation and production of chlorogenic acid Process for the separation and production of chlorogenic acid

C - Chemistry, Metallurgy

07

C

260/496.6

C07C 67/56 (2006.01) A23F 5/02 (2006.01) C07C 67/48 (2006.01) C07C 69/732 (2006.01)

Patent

CA 1292014

ABSTRACT Chlorogenic acid can be separated and produced as free acid or as salts thereof from plant raw material extracts by means of gel permeation chromatography on cross-linked modified polysaccharides, especially on dextrans. To obtain the free acid, the aqueous extract must be adjusted to a pH in the range of about 2 to 2.8. By use of a column of sufficient length the isomeric 5-, 4- and 3-chlorogenic acid can also be separated by the process of the invention.

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