Process for the stereoselective synthesis of 3-substituted...

C - Chemistry – Metallurgy – 07 – C

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C07C 317/44 (2006.01) C07C 315/00 (2006.01) C07C 315/02 (2006.01) C07C 315/04 (2006.01) C07D 263/26 (2006.01) C07F 7/08 (2006.01)

Patent

CA 2146144

Compounds of the formula I Image ¦ in which R1 and R2 are as defined can be prepared stereoselectively by reaction of acrylic acid or derivatives thereof or propionic acid or derivatives thereof with a chiral auxiliary, reaction with a mercaptan, stereoselective alkylation and subsequent hydrolysis and oxidation.

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