Process for the stereospecific synthesis of indole derivatives

Details Process for the stereospecific synthesis of indole derivatives Process for the stereospecific synthesis of indole derivatives

C - Chemistry, Metallurgy

07

D

260/306.1, 260/3

C07D 209/16 (2006.01) C07D 403/12 (2006.01) C07D 413/06 (2006.01)

Patent

CA 1298303

IN THE UNITED STATES PATENT & TRADEMARK OFFICE PATENT APPLICATION entitled: Process for the stereospecific synthesis of indole derivatives in the names of: Jean WAGNON Claude PLOUZANE Bernard TONNERRE Dino NISATO Assignee: SANOFI ABSTRACT OF DISCLOSURE The present invention relates to a process for the stereo- specific synthesis of indole derivatives of formula : Image (I) which consists in using 3-tosyloxy-1,2 0-isopropylidenepropane-1,2 -diol in an optically pure form in order to introduce the asymetric carbon C* of the compound (I).

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