Process for the stereospecific synthesis of leukotriene b4...

C - Chemistry – Metallurgy – 07 – F

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C07F 7/08 (2006.01) C07C 51/00 (2006.01) C07C 59/42 (2006.01)

Patent

CA 2124744

Procédé de synthèse stéréospécifique de leucotriène B4 (LTB4) de configuration 6Z, 8E, 10E de formule (Voir Figure 1) dans lequel on prépare un triéther dibenzoate auquel on fait subir une élimination réductrice selon le schéma (Voir Figure 2) de façon à obtenir un triéther que l'on transforme pour obtenir le leucotriène B4. Figure à publier : Figure 1

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