C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
195/45, 195/86
C12N 5/00 (2006.01) C07K 14/555 (2006.01) C12P 21/00 (2006.01)
Patent
CA 1147679
ABSTRACT OF THE DISCLOSURE This invention relates to a process for the surface culture of eukaryotic cells and in particular to such a process in which the cells are cultured on a solid carrier so dimensioned and disposed that when the culture medium 18 drained off, less than 8% of the culture medium (based on the bulk volume of the carrier minus the displacement volume) is retained by adhesion to the carrier. Preferred carriers include coils,spirals and saddle-shaped carriers. The process enables higher yields of cell culture dependent substances e.g. fibroblast interferon to be prepared by reducing adverse interfacial effects between the carriers.
354880
Fetherstonhaugh & Co.
Thomae (dr. Karl) G.m.b.h.
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