C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 41/30 (2006.01) C07C 39/38 (2006.01) C07C 41/24 (2006.01) C07C 253/30 (2006.01) C07C 255/54 (2006.01)
Patent
CA 2536768
A process for making a compound of formula I wherein R1, is CN, F or CI; R2 is H or Br; and R3 and R4 are each independently H or F. These compounds are useful in the treatment of chronic inflammatory diseases, such as rheumatoid arthritis.
L'invention concerne un procédé de préparation d'un composé de formule I, dans laquelle R¿1 ?représente CN, F ou CI; R¿2? désigne H ou Br; et R¿3? et R¿4? désignent de manière indépendante H ou F. Ces composés sont utiles dans le traitement de maladies inflammatoires chroniques, telles que la polyarthrite rhumatoïde.
Ghosh Mousumi
Levent Mahmut
Raveendranath Panolil
Ren Jianxin
Sutherland Karen Wiggins
Torys Llp
Wyeth
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