Process for the synthesis of 3-chloro-4-hydroxyacetanilide

Details Process for the synthesis of 3-chloro-4-hydroxyacetanilide Process for the synthesis of 3-chloro-4-hydroxyacetanilide

C - Chemistry, Metallurgy

07

C

260/557

C07C 233/25 (2006.01) C07C 231/12 (2006.01)

Patent

CA 1304407

71529-49 ABSTRACT OF THE DISCLOSURE A novel process for the preparation of 3-chloro-4- hydroxyacetanilide in high yields is disclosed which involves reacting N-acetyl-para-aminophenol (APAP) with sulfuryl chloride (SO2C12) as the chlorine source and liquid SO2 as the reaction medium.

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