Process for the synthesis of...

Details Process for the synthesis of... Process for the synthesis of...

C - Chemistry, Metallurgy

07

C

C07C 231/06 (2006.01)

Patent

CA 2710236

A process for preparing 3-amino-3-cyclobutylmethyl-2--hydroxypropionamide of the Formula I: [Chemical formula should be inserted here as it appears in the paper abstract.] or a salt thereof in- volves providing a compound of the Formula VI described herein in a solution comprising predominately dimethylsulfoxide (DMSO) and con-verting this compound directly to the compound of the Formula VIII described herein without working up or isolating the intermediate com-pound of the Formula VII described herein.

La présente invention concerne un procédé de préparation du 3-amino-3-cyclobutylméthyl-2-hydroxypropionamide de formule I : [la formule chimique devrait être insérée ici comme elle apparaît sur l'abrégé papier.] ou d'un de ses sels, comprenant les étapes consistant à fournir un composé de formule VI décrit ici dans une solution comprenant en majorité du diméthylsulfoxyde (DMSO) et à convertir ce composé directement en le composé de formule VIII décrit ici sans traiter ou isoler le composé intermédiaire de formule VII décrit ici.

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