Process for the synthesis of...

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C - Chemistry, Metallurgy

07

C

C07C 231/12 (2006.01) C07D 215/54 (2006.01) C07D 215/56 (2006.01) C07C 233/54 (2006.01)

Patent

CA 2475141

The invention claimed herein provides a process to oxidize N- (5-alkoxy-2- methyl-4-nitrophenyl) acetamides to N-acyl-2-amino-4-alkoxy-5-nitrobenzoic acids using potassium permanganate in the presence of magnesium sulfate in aqueous sulfolane or aqueous pyridine.

L'invention concerne un procédé permettant d'oxyder des acétamides N-(5-alcoxy-2-méthyl-4-nitrophényl) en acides N-acyl-2-amino-4-alcoxy-5-nitrobenzoïques au moyen du permanganate de potassium en présence du sulfate de magnésium dans du sulfolane aqueux ou de la pyridine aqueuse.

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