Process for the synthesis of (+) and...

Details Process for the synthesis of (+) and... Process for the synthesis of (+) and...

C - Chemistry, Metallurgy

07

C

C07C 255/46 (2006.01) C07C 211/29 (2006.01) C07C 215/08 (2006.01) C07C 215/20 (2006.01) C07D 209/52 (2006.01)

Patent

CA 2650658

The present invention is concerned with novel processes for the preparation of (+)-l-(3,4- dichlorophcnyl)'3-azabicyclo[3 1 0]hexane or a pharmaceutically acceptable salt thereof, and (-)- l-(3,4-dichloro.rho.henyl)-3-a2abicyclo[3 1.0)he.chi.ane or a pharmaceutically acceptable salt thereof. These compounds have pharmaceutical utility and are known to be usefi.il for treating e g, depression, anxiety disorders, eating disordeis and urinary incontinence

La présente invention concerne des procédés innovants de préparation de (+)-l-(3,4-dichlorophényl)-3-azabicyclo[3.1.0]hexane ou d'un sel pharmaceutiquement acceptable de celui-ci et de (-)-l-(3,4-dichloro.rho.hényl)-3-azabicyclo[3.1.0]hexane ou d'un sel pharmaceutiquement acceptable de celui-ci. Ces composés ont une utilité pharmaceutique et on sait qu'ils sont utilisables pour le traitement, par exemple, de la dépression, de l'angoisse, des troubles de l'alimentation et de l'incontinence urinaire.

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