Process for the synthesis of carbonucleoside and...

Details Process for the synthesis of carbonucleoside and... Process for the synthesis of carbonucleoside and...

C - Chemistry, Metallurgy

07

D

C07D 473/18 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2730622

Disclosed is a process for preparing a carbonucleoside of formula 1 and intermediates for use therein. The process involves the step of reacting a compound of formula 2 with a compound of formula 3 under Mitsunobu-type reaction conditions to obtain a compound of formula 4, wherein PG is a protecting group. The compound of formula 4 is deprotected to form the compound of formula 1, as shown below. (see formula 2) (see formula 3) (see formula 4) (see formula 1)

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