Process for the synthesis of leurosine and of its derivatives

C - Chemistry – Metallurgy – 07 – D

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260/237.3

C07D 519/04 (2006.01)

Patent

CA 1101414

ABSTRACT The present invention relates to the synthesis of leurosine and of its derivatives. In this process, the .DELTA. 15' (20') dehydroxy-20'- vincaleucoblastine derivative corresponding to the product which is to be synthesised is oxidised in the presence of all oxidising metal salt, air or oxygen. The products obtained are useful in the pharmaceutical industry.

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