Process for the synthesis of novel and known nitroimidazoles...

Details Process for the synthesis of novel and known nitroimidazoles... Process for the synthesis of novel and known nitroimidazoles...

C - Chemistry, Metallurgy

07

D

167/233, 260/304

C07D 233/91 (2006.01) A61K 31/41 (2006.01) C07D 403/06 (2006.01) C07D 413/06 (2006.01)

Patent

CA 2003868

ABSTRACT The present invention is novel nitroimidazoles useful as radiosensitizing or chemosensitizing agents in the treatment of hypoxic tumor cells. Also, the present invention is a novel process for preparing both known and novel nitroimidazoles having novel intermediates. The process advantageously reduces the number of process steps, provides increased yield with both greater safety and greater control of stereo- isomerism in the products.

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