Process for the synthesis of rocuronium bromide

Details Process for the synthesis of rocuronium bromide Process for the synthesis of rocuronium bromide

C - Chemistry, Metallurgy

07

J

C07J 71/00 (2006.01) C07J 43/00 (2006.01)

Patent

CA 2617816

The invention encompasses processes for synthesizing l-[17.beta.-acetyloxy-3.alpha.- hydroxy-2.beta.-(4-morpholmyl)-5.alpha.-androstan-16.beta.-yl]-l-(2-propenyl)pyrrolidinium bromide (rocuronium bromide) and intermediates thereof.

L'invention concerne des procédés pour synthétiser du l-[17ß-acétyloxy-3a- hydroxy-2ß-(4-morpholmyl)-5a-androstane-16ß-yl]-l-(2-propényl)pyrrolidinium bromure (bromure de rocuronium), ainsi que ses intermédiaires.

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