Process for the synthesis of semi-synthetic...

Details Process for the synthesis of semi-synthetic... Process for the synthesis of semi-synthetic...

C - Chemistry, Metallurgy

08

B

C08B 37/10 (2006.01) C08B 37/00 (2006.01)

Patent

CA 2114862

A process for the synthesis of semi-synthetic glycosaminoglycans of general formula III (see fig. I) with heparin or heparan structure modified in position 2 of the .alpha.-L-iduronic-2-O-sulfate acid in which the sulfate group is, entirely or in part, substituted with a nucleophilic radical is described. Said process is carried out by treating glycosaminoglycans with heparin or heparan structure by means of a nucleophilic agent in alkaline medium.

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