Process for the synthesis of sulfonyl halides and...

Details Process for the synthesis of sulfonyl halides and... Process for the synthesis of sulfonyl halides and...

C - Chemistry, Metallurgy

07

C

C07C 303/22 (2006.01) C07C 303/38 (2006.01) C07D 209/22 (2006.01)

Patent

CA 2610228

The present invention provides synthetic processes for the preparation of sulfonyl halides of Formula Ar- (R) 2-SO2-X and sulfonamides of Formula Ar- (R)2-SO2- NR4R5, where the constituent variables are as defined herein, that are useful as intermediates in the preparation of pharmaceuticals. The sulfonyl halides are prepared by reacting a sulfonic acid salt with a halogen substitution reagent in the presence of a catalytic amount of water and in the presence of a co-catalyst . The so prepared halides can than be further reacted with an amine to obtain the sulfonamides.

L'invention concerne des procédés de synthèse destinés à la préparation d'halogénures de sulfonyle de formule Ar-(R)2-SO2-X et de sulfonamides de formule Ar-(R)2-SO2- NR4R5, les variables constituantes étant telles que définies dans la description, et utiles en tant qu'intermédiaires dans la préparation de produits pharmaceutiques.

Affiliated with

Also associated with

Rating

Process for the synthesis of sulfonyl halides and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the synthesis of sulfonyl halides and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the synthesis of sulfonyl halides and... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1813168