Process for the synthesis of the nicotinyl ester of 6-...

Details Process for the synthesis of the nicotinyl ester of 6-... Process for the synthesis of the nicotinyl ester of 6-...

C - Chemistry, Metallurgy

07

D

260/279.6

C07D 213/80 (2006.01)

Patent

CA 1167852

IV. Abstract of Invention: 6-Aminonicotinic acid is reacted with an alkali car- bonate selected from the group consisting of sodium car- bonate and potassium carbonate. The reaction is carried out at elevated temperature and in dimethylformamide. The 6-aminonicotinic acid alkali salt so produced is reacted with 3-chloromethylpyridine hydrochloride. The reaction is carried out at elevated temperature and in dimethyl- formamide. The desired nicotinyl ester is thus produced.

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