Process for the virus-inactivation of immunoglobulin

Details Process for the virus-inactivation of immunoglobulin Process for the virus-inactivation of immunoglobulin

A - Human Necessities

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A61L 2/04 (2006.01) A61K 39/395 (2006.01) A61L 2/00 (2006.01) C12N 7/04 (2006.01)

Patent

CA 1268707

ABSTRACT OF THE DISCLOSURE Virus-contaminated immunoglobulin can be virus- inactivated by heating it in a substantially dry state at a temperature of 30° to 100°C for a period of time suf- ficient for inactivating virus with maintaining original activity of the immunoglobulin. The addition of glycine, sodium chloride, sodium acetate, polyethylene glycol, albumin or mannitol enhances the effect and gives good solubility and good state to the solution of the virus- inactivated immunoglobulin.

491110

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