Process for the whole broth extraction of avermectin

Details Process for the whole broth extraction of avermectin Process for the whole broth extraction of avermectin

C - Chemistry, Metallurgy

07

H

195/71, 260/230.

C07H 17/08 (2006.01) C07H 19/01 (2006.01) C12P 19/62 (2006.01)

Patent

CA 1185198

TITLE OF THE INVENTION PROCESS FOR THE WHOLE BROTH EXTRACTION OF AVERMECTIN ABSTRACT OF THE DISCLOSURE A process for the whole broth extraction of avermectins wherein the pH of the whole broth is adjusted with mineral acid and then contacted with a solvent extractant so that the avermectic active component is taken up by the solvent. The now avermectin rich extractant is then processed through a solvent concentration step and the avermectin isolated by conventional crystallization. The extractant is then recycled with appropriate make-up to extract a subsequent batch of whole broth.

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