C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
530/5.06
C07D 209/52 (2006.01) C07D 209/42 (2006.01) C07D 209/54 (2006.01) C07K 5/02 (2006.01) C07K 5/06 (2006.01)
Patent
CA 1317067
ABSTRACT The invention relates to a process for the preparation of optically pure compounds of the general formula IIa or IIb Image (IIa) Image (IIb) in which A, B1, B2, C, R1, R2, X, Y and Z have the indicated meanings, which comprises reacting, in the presence of a condensing agent or, where appropriate, as an active ester, optically pure compounds of the formula Ia or Ib Image Image (Ia) (Ib) in which A, B1, B2, C and R have the indicated meanings with optically pure compounds of the formula III (III) Image in which R, R1, R2, X, Y and Z have the indicated meanings, splitting off the radical R by hydrogenolysis or hydrolysis, and, where appropriate, converting the optically pure compounds of the formula Ia or Ib into physiologically tolerated salts.
576609
Geiger Rolf
Henning Rainer
Langner Dietrich
Teetz Volker
Urbach Hansjorg
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sanofi-Aventis Deutschland Gmbh
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