Process for waste nitrogen removal

Details Process for waste nitrogen removal Process for waste nitrogen removal

A - Human Necessities

61

K

167/262

A61K 31/19 (2006.01)

Patent

CA 1221636

ABSTRACT OF THE DISCLOSURE A method of alleviating the accumulation of waste nitrogen in human beings is disclosed, wherein phenyl- butyrate, or even numbered conger thereof, is adminis- tered to a patient having such waste nitrogen accumula- tion. The phenylbutyrate or other compound is broken down by beta-oxidation to eventually yield phenylacetate, which is known to be useful for removing waste nitrogen from the blood stream. The present invention provides a solution to the offensive odor of phenylacetate,which is unpalatable to patients, and also can eliminate peaks and valleys of drug levels in the patient, due to the gradual formation of the desired compound phenylacetate in the patient's body.

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