Process fro preparing 4-pyrimidinones

C - Chemistry – Metallurgy – 07 – D

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C07D 403/10 (2006.01) C07D 239/36 (2006.01) C07D 403/14 (2006.01)

Patent

CA 2091614

- 14 - ABSTRACT NEW PROCESS FOR PREPARING 4-PYRIMIDINONES A compound represented by formula (VII) Image (VII) in which R1 represents a substituent selected from unbranched or branched C1-7 alkyl, unbranched or branched C3-9 alkenyl, and (C3- 7) cycloalkyl(C1-6)alkyl, R2 represents a substituent selected from hydrogen, unbranched or branched C1-7 alkyl, (C3-7)cycloalkyl(C1-3)alkyl, aryl(C1- 3)alkyl optionally substituted on the ring-system, aryloxy(C1- 3)alkyl optionally substituted on the ring-system, arylthio(C1- 3)alkyl optionally substituted on the ring-system, arylsulphonyl(C1-3)alkyl optionally substituted on the ring- system, and heteroaryl(C1-3)alkyl optionally substituted on the ring-system. A compound of formula (VII) may be used in a process for preparing a compound represented by formula (I) - 15 - Image (I) in which R1 and R2 are as defined above, which process comprises deprotecting a compound represented by formula (VII) as defined above.

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