C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 279/18 (2006.01) C07D 265/38 (2006.01)
Patent
CA 2707902
A method of forming a 3-phenylimino-3H-phenothiazine or a 3-phenylimino-3H- phenoxazine mediator includes providing a first reactant including phenothiazine or phenoxazine, providing a first solvent, providing a second reactant and providing a second solvent. The first reactant, first solvent, second reactant and second solvent are combined to form a reactants solution. Sodium persulfate is added to the reactants solution to couple the first and second reactants resulting in a reaction solution including the 3-phenylimino-3H-phenothiazine or the 3-phenylimino-3H-phenoxazine mediator.
L'invention porte sur un procédé de fabrication d'un médiateur de 3-phénylimino-3H-phénothiazine ou de 3-phénylimino-3H-phénoxazine, qui comprend la fourniture d'un premier réactif comprenant de la phénothiazine ou de la phénoxazine, la fourniture d'un premier solvant, la fourniture d'un second réactif et la fourniture d'un second solvant. Le premier réactif, le premier solvant, le second réactif et le second solvant, sont combinés pour former une solution de réactifs. Du persulfate de sodium est ajouté à la solution de réactifs pour coupler les premier et second réactifs résultants dans une solution de réaction comprenant le médiator de 3-phénylimino-3H-phénothiazine ou de 3-phénylimino-3H-phénoxazine.
Arndt Henry C.
Marfurt Karen L.
Bayer Healthcare Llc
Osler Hoskin & Harcourt Llp
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