Process of making dosage units by wet granulation

Details Process of making dosage units by wet granulation Process of making dosage units by wet granulation

A - Human Necessities

61

K

A61K 31/565 (2006.01) A61K 9/20 (2006.01) A61P 5/34 (2006.01)

Patent

CA 2200754

The invention relates to a process of making pharmaceutical dosage units comprising at least desogestrel or Org 30659 (17.alpha.--17-hydroxy-11-methylene-19-norpregna-4,15-dien-20-yn-3-one), present in an amount of about 0.005 to 1.0 percent by weight of each pharmaceutical dosage unit, characterized in that the steroidal agent, and when required pharmaceutically acceptable excipients, are mixed with water and granulated.

L'invention concerne un procédé de préparation d'unités posologiques pharmaceutiques comprenant au moins du désogestrel ou Org 30659 (17 alpha -17-hydroxy-11-méthylène-19-norprégna-4,15-dién-20-yn-3-one), présent dans une quantité comprise entre environ 0,005 et 1,0 pour-cent en poids du poids de chaque unité posologique, ce procédé étant caractérisé en ce que l'agent stéroïdien et, lorsqu'ils sont nécessaires, les excipients acceptables sur le plan pharmacologique, sont mélangés à de l'eau puis granulés.

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