A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/39 (2006.01) A61K 31/715 (2006.01) A61L 24/08 (2006.01) A61L 24/10 (2006.01) B01F 3/04 (2006.01)
Patent
CA 2534897
The present invention is directed to processes of making flowable hemostatic compositions and devices that include the flowable hemostatic composition disposed therein, where a volume of biocompatible liquid, a volume of a biocompatible gas, and an amount of solid particles of a biocompatible polymer are mixed together to form a substantially homogenous composition including a discontinuous gas phase and the solid particles substantially homogenously dispersed throughout a continuous liquid phase to form a flowable hemostatic composition, and the composition then transferred into a device suitable for applying the flowable hemostatic composition to a site of a body requiring hemostasis under conditions effective to maintain the substantially homogenous dispersion of the gas phase and the solid particles throughout the liquid phase.
La présente invention concerne des procédés permettant de fabriquer des compositions hémostatiques fluides, et des dispositifs contenant cette composition hémostatique fluide. Un volume d'un liquide biocompatible, un volume d'un gaz biocompatible et une quantité de particules solides d'un polymère biocompatible sont mélangés ensemble de manière à former une composition sensiblement homogène contenant une phase gazeuse discontinue, les particules solides étant dispersées de manière sensiblement homogène à travers une phase liquide continue pour former une composition hémostatique fluide. La composition est ensuite transférée dans un dispositif conçu pour permettre l'application de cette composition sur un site d'un corps nécessitant une hémostase dans des conditions efficaces pour conserver la dispersion sensiblement homogène de la phase gazeuse et les particules solides à travers la phase liquide.
Craven Thomas Lee
Gorman Anne J.
Looney Dwayne Lee
Pendharkar Sanyog M.
Rivera Ada
Ethicon Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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