A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/234
A61K 31/425 (2006.01) A61K 9/08 (2006.01) C07D 275/00 (2006.01)
Patent
CA 1184495
ABSTRACT OF THE DISCLOSURE By the addition of L-aspartic acid, the solubility of Famotidine in water can be effectively improved for providing a stable aqueous solution of Famotidine for injection. A lyophilized composition of Famotidine for injection is also prepared by lyophilizing an aqueous solution containing Famotidine together with L-aspartic acid and/or L-glutamic acid. Mannitol may be also added to the aqueous solution. as an excipient.
417637
Aruga Masayoshi
Nakajima Norio
Saisho Norishige
Johnson Douglas S. Q.c.
Yamanouchi Pharmaceutical Co. Ltd.
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