Process to make a sustained release formulation

Details Process to make a sustained release formulation Process to make a sustained release formulation

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61K 9/16 (2006.01) A61K 38/08 (2006.01) A61K 47/34 (2006.01)

Patent

CA 2380902

This invention pertains to a process for making a sustained release complex, Compound (I), which comprises Compound (A), having formula (A), and a copolymer comprising poly-(1)-lactic-glycolic-tartaric acid (P(1)LGT), wherein the amino group of Compound (A) is ionically bound to a carboxyl group of the P(1)LGT.

L'invention concerne un procédé de fabrication d'un complexe à libération lente, le composé (I), qui contient un composé (A), représenté par la formule (A) et un copolymère contenant un acide poly-(1)-lactique-glycolique-tartarique (P(1)LGT), dans lequel le groupe aminé du composé (A) est lié ioniquement à un groupe carboxyle du P(1)LGT.

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