Process to prepare n-(2-hydroxyalkyl)-n- phosphonomethylglycine

C - Chemistry – Metallurgy – 07 – F

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C07F 9/38 (2006.01)

Patent

CA 2080979

39-21(2662)A ABSTRACT PROCESS FOR THE PREPARATION OF N-HYDROXYALKYL- N-PHOSPHONOMETHYLGLYCINE An efficient process is disclosed for the preparation of N-(2-hydroxyalkyl)-N-phosphonomethyl- glycine represented by the formula Image which comprises heating, preferably to reflux, an aqueous solution of glyoxal and N-(2-hydroxyalkyl)amino- methylphosphonic acid represented by the formula Image wherein R and R1 are individually hydrogen, an alkyl having 1 to 4 carbon atoms, or aryl. Preferably both R and R1 are hydrogen.

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