Processed tissue for medical device formation

A - Human Necessities – 61 – L

Patent

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A61L 27/36 (2006.01) A61F 2/24 (2006.01)

Patent

CA 2487989

In some embodiments, a method for processing tissue comprises the application of a directional load to modify the properties of the tissue. In particular, the directional force is sufficient to increase the rigidity of the tissue asymmetrically relative to an unaligned tissue equivalently processed without being subjected to a load. In some embodiments, a sufficient directional load is applied to increase the rigidity of the tissue relative to an unaligned tissue equivalently processed that is not subjected to the load, in which the load is applied with a load applicator. A connector transfers the load from the load applicator to the tissue. Selectively aligned tissue having asymmetric mechanical properties can be used to form a prosthetic valve. The leaflets are matched with respect to each of their properties to have improved coaptation relative to corresponding tissue leaflets that are not aligned.

L'invention concerne, suivant certaines formes d'exécution, un procédé de traitement d'un tissu comprenant l'application d'une charge directionnelle en vue de modifier les propriétés du tissu. En particulier, la force directionnelle est suffisante pour accroître la rigidité du tissu de façon asymétrique par rapport à un tissu non aligné, traité de façon équivalente, sans être soumis à une charge. Dans certaines formes d'exécution, une charge directionnelle suffisante est appliquée pour accroître la rigidité du tissu par rapport à un tissu non aligné traité de façon équivalente et qui n'est pas soumis à la charge, ladite charge étant appliquée au moyen d'un applicateur de charge. Un connecteur transfert la charge de l'applicateur au tissu. Un tissu sélectivement aligné, doté de propriétés mécaniques asymétriques peut être utilisé pour former une valve prothétique. Les valves sont adaptées, eu égard à chacune de leurs propriétés, de manière à avoir une coaptation améliorée vis-à-vis de valves en tissu correspondantes qui ne sont pas alignées.

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