Processes and compositions for methylation-based enrichment...

Details Processes and compositions for methylation-based enrichment... Processes and compositions for methylation-based enrichment...

C - Chemistry, Metallurgy

12

N

C12N 15/10 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2737200

L'invention concerne des compositions et des procédés qui emploient des régions génomiques dont la méthylation est différente selon qu'ils proviennent d'une mère ou de son ftus, en vue de séparer ou isoler un acide nucléique ftal dans un échantillon maternel ou d'enrichir cet échantillon en acide nucléique ftal. Les compositions et les procédés décrits dans l'invention sont utiles pour les diagnostics prénatals non invasifs, notamment la détection d'aneuploïdies chromosomiques.

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