C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/205, 260/356
C07D 309/12 (2006.01) A61K 31/55 (2006.01) C07C 405/00 (2006.01) C07D 307/20 (2006.01) C07F 7/18 (2006.01)
Patent
CA 1267892
ABSTRACT OF THE DISCLOSURE This invention relates to a process for making a compound of formula I Image (I) in the form of a stereoisomer or mixture thereof, wherein R is hydrogen, lower alkyl; X is hydrogen, halo, trifluoromethyl, lower alkyl or lower alkoxy, and the wavy lines represent the .alpha. or .beta. configuration with the proviso that when one wavy line is .alpha. the other is .beta., or a pharmaceutically acceptable, non-toxic salt of the compound wherein R is hydrogen; novel intermediates useful for preparing these compounds; processes for making the intermediates; and a stereoisomer of the compound of formula I wherein R is methyl and X is hydrogen and a process for making same.
470699
Beard Colin C.
Cooper Gary F.
Li Tsung-Tee
Van Horn Albert R.
Wren Douglas L.
Beard Colin C.
Cooper Gary F.
Johnson Douglas S. Q.c.
Li Tsung-Tee
Syntex (u.s.a.) Inc.
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