C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 231/20 (2006.01) C07C 237/04 (2006.01) C07C 247/04 (2006.01) C07D 303/48 (2006.01)
Patent
CA 2646123
This invention relates to processes and intermediates for the preparation of an alpha- amino beta-hydroxy acid of Formula (1) wherein the variables R1 R~1 and R2 are defined herein and the compound of Formula (1) has an enantiomeric excess (ee) of 55% or greater.
La présente invention concerne des procédés et des intermédiaires pour la synthèse d'un alpha-amino-bêta-hydroxyacide de formule (1) où les variables R1, R'1 et R2 sont telles que définies dans la présente invention, le composé de formule (1) présentant un excès énantiomérique (ee) supérieur ou égal à 55 %.
Chen Minzhang
Forslund Raymond E.
Jung Young Chun
Tanoury Gerald J.
Gowling Lafleur Henderson Llp
Vertex Pharmaceuticals Incorporated
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