Processes and intermediates for the preparation of...

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C - Chemistry, Metallurgy

07

D

C07D 333/34 (2006.01) C07C 45/51 (2006.01) C07C 47/52 (2006.01) C07C 47/546 (2006.01) C07C 251/24 (2006.01) C07C 251/86 (2006.01) C07D 307/38 (2006.01) C07D 307/52 (2006.01) C07D 307/58 (2006.01) C07D 307/64 (2006.01) C07D 333/06 (2006.01) C07D 333/32 (2006.01)

Patent

CA 2132639

2132639 9319033 PCTABS00025 Processes for preparing 2-substituted benzaldehydes of general formula (I), wherein: R1 is CH2CH2-(L1)p-(CH2)q-(L2)r-CH2-(T)s-Z; L1 and L2 are independently CH2CH2, CH=CH or C=C; q is 0 to 8; p, r and s are independently 0 or 1; T is O, S, CH2, CH=CH, C=C; and Z is C1-4alkyl, ethynyl, trifluoromethyl, isopropenyl, furanyl, thienyl, cyclohexyl or phenyl optionally mono substituted with CF3, C1-4alkyl, C1-4alkoxy, methylthio, or trifluoromethylthio; and R2 and A are independently H, CF3, C1-4alkyl, F, Cl, Br or I; are useful for preparing pharmaceutically active compounds.

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