C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 405/12 (2006.01) C07B 43/04 (2006.01) C07B 57/00 (2006.01)
Patent
CA 2559303
The invention relates to processes such as that shown in the scheme and compounds useful for producing modified aspartic acid derivatives, such as aspartic acid aldehyde moieties. Aspartic acid derivatives are useful for preparing caspase inhibitors and/or prodrugs thereof.
La présente invention concerne des procédés et des composés utilisés pour produire des dérivés d'acide aspartique modifiés, tels que des groupes aldéhyde d'acide aspartique. Ces dérivés d'acide aspartique sont utilisés pour préparer des inhibiteurs de caspase et/ou des promédicaments à base de ceux-ci.
Chen Minzhang
Guerin David J.
Jones Andrew D.
Nyce Philip L.
Snoonian John R.
Gowling Lafleur Henderson Llp
Vertex Pharmaceuticals Incorporated
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