C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 309/24 (2006.01) C07C 69/76 (2006.01) C07C 229/06 (2006.01) C07C 229/12 (2006.01) C07D 487/04 (2006.01)
Patent
CA 2304656
The present application relates to a series of novel sulfonic acid metal cation salts of formula (I) which are useful intermediates to prepare antifolate 5-substituted pyrrolo[2,3-d]pyrimidines. The present invention also relates to a novel process for preparing the sulfonic acid metal cation salts and to a novel process for preparing aldehydes of formula (II) from the corresponding sulfonic acid metal cation salts.
La présente invention concerne un ensemble de nouveaux sels de cations métalliques d'acide sulfonique représentés par la formule (I), qui constituent des intermédiaires convenant particulièrement à la préparation d'antifoliques pyrrolo[2,3-d]pyrimidines 5-substitués. La présente invention concerne également un nouveau procédé de préparation de sels de cations métalliques d'acide sulfonique et un nouveau procédé de préparation d'aldéhydes représentés par la formule (II) à partir des sels de cations métalliques d'acide sulfonique correspondants.
Barnett Charles Jackson
Kjell Douglas Patton
Slattery Brian James
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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