Processes and intermediates useful to make antifolates

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 255/00 (2006.01) C07D 207/02 (2006.01) C07D 211/04 (2006.01) C07D 213/02 (2006.01) C07D 231/02 (2006.01) C07D 231/04 (2006.01) C07D 231/06 (2006.01) C07D 231/10 (2006.01) C07D 233/02 (2006.01) C07D 233/04 (2006.01) C07D 233/54 (2006.01) C07D 237/02 (2006.01) C07D 237/04 (2006.01) C07D 237/06 (2006.01) C07D 239/02 (2006.01) C07D 239/04 (2006.01) C07D 239/06 (2006.01) C07D 239/20 (2006.01) C07D 239/24 (2006.01) C07D 241/02 (2006.01) C07D 241/06 (2006.01) C07D 241/10 (2006.01) C07D 261/02 (2006.01) C07D 2

Patent

CA 2319424

The present invention concerns intermediates, and processes directed to and from those intermediates, to a series of pyrimidine derivatives of formula (V), which are intermediates to useful antifolate compounds or are themselves useful antifolate compounds.

L'invention concerne des intermédiaires et des procédés de fabrication et d'utilisation desdits intermédiaires, une série de dérivée de pyrimidine, de formule (V), qui sont des intermédiaires de composés antifoliques utiles ou qui sont eux-mêmes utiles en tant que composés antifoliques.

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